Myeloproliferative neoplasms: Morphology and clinical practice
نویسندگان
چکیده
منابع مشابه
JAK2 mutations and clinical practice in myeloproliferative neoplasms.
With the discovery in the last 3 years of novel Janus kinase 2 (JAK2) and thrombopoietin receptor (MPL) mutations, the pathogenetic understanding of and clinical practice for myeloproliferative neoplasms (MPNs) have entered a new era. Each one of these newly discovered mutations, including JAK2V617F, MPLW515L, and a JAK2 exon 12 mutation, has been shown to result in constitutive activation of J...
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A. M. Vannucchi1, T. Barbui2, F. Cervantes3, C. Harrison4, J.-J. Kiladjian5, N. Kröger6, J. Thiele7 & C. Buske8, on behalf of the ESMO Guidelines Committee* Department of Experimental and Clinical Medicine, University of Florence, Florence; Hematology and Foundation for Research, Ospedale Papa Giovanni XXIII, Bergamo, Italy; Department of Hematology, Hospital Clínic, IDIBAPS, University of Barc...
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According to the World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues, myelodysplastic/myeloproliferative neoplasms are clonal myeloid neoplasms that have some clinical, laboratory, or morphologic findings that support a diagnosis of myelodysplastic syndrome, and other findings that are more consistent with myeloproliferative neoplasms. These disorders ...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2016
ISSN: 0361-8609
DOI: 10.1002/ajh.24288